Aggressive genomic features in clinically indolent primary HHV8-negative effusion-based lymphoma
نویسندگان
چکیده
منابع مشابه
Aggressive and Hiv-negative Hhv8-unrelated Primary Effusion-like Lymphoma with T-cell Phenotype: a Rare Case Report
Introduction: Primary effusion lymphoma (PEL) is a rare type of non-Hodgkin’s lymphoma, which is characterized by serous effusion in body cavities without detectable tumor masses or lymphadenopathy. It is usually found in human herpes virus 8 (HHV8) and human immunodeficiency virus (HIV) positive patients, and tumor cells usually show a B-cell–lineage immunophenotype. Case presentation: In the ...
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Primary effusion lymphoma (PEL) is a rare extranodal lymphoma that typically presents in a body cavity in the absence of a detectable tumor mass and that occurs predominantly in immunosuppressed individuals. The neoplastic lymphoid cells are frequently infected with human herpes virus 8 (HHV8), also known as Kaposi sarcoma herpes virus (KSHV). We describe two HIV-negative patients who presented...
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Recent molecular evidence suggests an association with a new herpesvirus, Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8), and primary effusion lymphomas (PELs). PELs have a characteristic morphology, phenotype, and clinical presentation, with malignant effusions in the absence of a contiguous solid tumor mass. We have established a cell line (KS-1) from a KSHV-positive human immunodeficie...
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Primary effusion lymphoma (PEL) is a rare HIV-associated non-Hodgkin's lymphoma (NHL) that accounts for approximately 4% of all HIV-associated NHL. PEL has a unique clinical presentation in having a predilection for arising in body cavities such as the pleural space, pericardium, and peritoneum. PEL cells are morphologically variable with a null lymphocyte immunophenotype and evidence of human ...
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We report two cases of aggressive thyroid lymphoma in elderly patients that presented as Epub ahead of print large infiltrative thyroid masses with extensive invasion to adjacent structures including trachea, esophagus, and common carotid artery. Ultrasonography displayed irregular shaped, heterogeneous hypoechoic mass, mimicking anaplastic carcinoma. Computed tomography showed heterogeneously ...
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ژورنال
عنوان ژورنال: Blood
سال: 2019
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2017-12-822171